Keywords :
Celastraceae; Siphonodon celastrineus; Lupanes; Friedelanes; Oleananes; Ursanes; Triterpenes; NMR Spectroscopy; Cytotoxic Activities
บทคัดย่อ :
Twenty-one triterpenes consisting of a lupane derivative, two friedelanes, an oleanane derivative, and 17 ursane-type triterpenoids, together with three known triterpenes, three sterols, a fatty acid, a sesquiter-pene alkaloid, and a glycerol derivative, were isolated from the stem of Siphonodon celastrineus. Their structures were characterized by various spectroscopic techniques, as well as comparison with literature data. Twenty-seven metabolites of these were evaluated for cytotoxic activity against six human cancer cell lines. The biosynthetic formation of a 1,4-dioxane bridge is also discussed.
เอกสารอ้างอิง :
Kaweetripob, W., Mahidol, C., Prawat, H., & Ruchirawat, S. (2013). Lupane, friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. Phytochemistry, 96, 404-417.
