Keywords :
Celastraceae,
Siphonodon celastrineus,
Lupanes,
Friedelanes,
Oleananes,
Ursanes,
Triterpenes,
NMR spectroscopy,
Cytotoxic activities
บทคัดย่อ :
Twenty-one triterpenes consisting of a lupane derivative, two friedelanes, an oleanane derivative, and 17
ursane-type triterpenoids, together with three known triterpenes, three sterols, a fatty acid, a sesquiter-
pene alkaloid, and a glycerol derivative, were isolated from the stem of Siphonodon celastrineus. Their
structures were characterized by various spectroscopic techniques, as well as comparison with literature
data. Twenty-seven metabolites of these were evaluated for cytotoxic activity against six human cancer
cell lines. The biosynthetic formation of a 1,4-dioxane bridge is also discussed.
เอกสารอ้างอิง :
Kaweetripob, W., Mahidol, C., Prawat, H., & Ruchirawat, S. (2013). Lupane, friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. Phytochemistry, 96, 404-417.
