Keywords :
Hair conditioner; Phyllanthus emblica; Zanthoxylum limonella; Anti-inflammation; Antioxidation
บทคัดย่อ :
Hair conditioner is a hair care product that is applied after shampooing in order to condition the hair and then rinsed out. The product is beneficial to dry or damaged hair. It works by restoring moisture, and smoothing the cuticles of the hair follicles . Ultraviolet and visible radiations are known to damage hair involving hair color changes and protein damage. It can cause permanent damage to the cuticle, which is the outside covering of the hair. It can penetrate into the cortex, which is the center of the hair, and do all sorts of damage, uv breaks chemical bonds and cause dryness, rough texture, split ends, susceptibility to breakage, unmanageability, and loss of pigmentation and luster. This research aimed to develop an anti-microbial, antioxidant and anti-inflammatory benefits hair conditioner for damaged hair and nourish the scalp, comprising a patented mixed extract from fruits of Phyllanthus emblica and Zanthoxylum limonella. The extract s antioxidant effect will help reducing hair damage from free radicals causing by pollutants and uv rays. Hair and scalp health could be promoted by the anti-microbial and anti-inflammatory effects of the extract. Phyllanthus emblica L. (EUPHORBIACEAE), or Ma-khampom, is an herbal plant commonly found in Thailand. The edible fruit was reported as an alternative treatment of skin disorders, inflammations and premature graying. Chemical constituents of the fruit include vitamin c, gibberellins, lupeol, kaempferol, quercetin, emblicain A and B, punigluconin, pedunculaginn, phyllanthin, zeatin, amlaic acid, corilagin ellagic acid, putranjivain A, digalic acid, phyllembolic acid, emblicol and galactaric acid3. The fruit also has antioxidant activity, which provides protection against free radicals induced by uv4. We have found that the ethanol fruit extract of P.emblica was effective as an anti-microbial (MIC 10-20 mg/ml) and antioxidant (EC5018.7 pg/ml). Zanthoxylum limonella Alston (RUTACEAE), or Ma-khwaen, is widely distributed in the northern part of Thailand. Dry fruits are sold in local markets and traditionally used as spice. Its essential oil exhibits the anti-oxidative potential. The oil contains Sabinene which is a potent bactericidal against the multi-drug resistant bacteria 5 7. We have reported that the ethanol fruit extract of z. limonella is effective against tested microbial including c . albicans (MIC 2.5-10 mg/ml) and is an anti-oxidant (EC50 5.9 pg/ml) with total flavonoids of 3.61 mg rutin/g extract8. The patented mixed extract from fruits of p. emblica and z. limonella is effective as an anti-oxidant (EC50
7.9 pg/ml) and in vitro anti-microbial (MIC 4.5 mg/ml) against Propionibacterium acne, Staphylococcus
aureus, ร. epidermidis and Streptococcus pyogenes9. The mixed extract was used to develop a patented
hair conditoner for antioxidant benefits and to nourish the hair and scalp.
เอกสารอ้างอิง :
Potduang, B., Keeta, I., Saisin, W., Wannaphatchaiyong, S. and Fungsin, B., (2013). Development of hair conditoner comprising a mixed extract from fruits of Phyllanthus emblica and Zanthoxylumlimonella. The Thai Journal of Pharmaceutical Sciences, 38, pp.209-211.
