Keywords :
Clausena; Clausena excavata; Rutaceae; Clauslactone E; Heptazolin; Geographic and Chemical Diversity
บทคัดย่อ :
Methanolic crude extracts obtained from leaves, stem bark and root bark of 57 accessions of Clausena excavata, C. harmandiana, of both varieties of C. wallichii, as well as of three unidentified Clausena samples, were analysed for the presence of coumarins and carbazoles. All accessions were collected from different locations all over Thailand. HPLC coupled with UV-DAD was applied for phytochemical profiling. Structures of known pyranocoumarins 1-4 and of coumarins 5-8 bearing an O-geranyl moiety, as well as of carbazoles 9-12 were confirmed by NMR and MS spectroscopy, respectively. Observed chemical diversification in the studied samples is discussed in relation to geographic distribution and with respect to organ-specific accumulation. Chemotaxonomic significance is briefly addressed.
เอกสารอ้างอิง :
Wongthet, N., Sanevas, N., Schinnerl, J., Valant-Vetschera, K., Bacher, M., & Vajrodaya, S. (2018). Chemodiversity of Clausena excavata (Rutaceae) and related species: Coumarins and carbazoles. Biochemical Systematics and Ecology, 80, 84-90.
