Keywords :
Xylopia pierrei, Heptenes, Cytotoxic activity, Small cell lung cancer
บทคัดย่อ :
Phytochemical investigation of the stem bark of
Xylopia pierrei Hance led to the isolation of one triterpene,
polycarpol (1), three heptenes, (7R)-acetylmelodorinol (2),
(7R)-melodorinol (3), and melodienone (8), and four flavonoids,
pinocembrin (4), isochamanetin (5), chrysin (6),
and dichamanetin (7). All compounds were isolated for the
first time from this plant species. The structures of the
isolated compounds were characterized by spectroscopic
techniques and by comparison of the spectroscopic data
with the literature values and the stereochemistry at the
asymmetric carbon was determined by the modified
Mosher
เอกสารอ้างอิง :
Chokchaisiri, R., Kunkaewom, S., Chokchaisiri, S., Ganranoo, L., Chalermglin, R., & Suksamrarn, A. (2017). Potent cytotoxicity against human small cell lung cancer cells of the heptenes from the stem bark of Xylopia pierrei Hance. Medicinal Chemistry Research, 26(6), 1291-1296.
